United States: Xenotransplantation represents a scientific advance through Chinese researchers who successfully conducted a transplant of a genetically modified pig kidney into a human subject. Scientists have demonstrated through their findings that pig liver transplants may prove feasible for future medical applications.
A Third Successful Pig Kidney Transplant
A Chinese patient survived as the third individual worldwide who received a kidney transplant from a genetically modified pig. The patient received the surgical procedure conducted by Dr. Lin Wang and Xijing Hospital about three weeks ago and now shows signs of good recovery progress. The functioning kidney demonstrates progress in resolving the human organ shortage crisis, as reported by Associated Press.
A Chinese medical team has successfully transplanted a gene-engineered pig kidney into a 69-year-old end-phase uremic patient, marking a major clinical milestone in cross-species organ transplantation.
— China Science (@ChinaScience) March 18, 2025
The female patient was stable with good kidney function on the sixth day… pic.twitter.com/DC0SijQ3mf
Pig Livers May Be Next
In a separate experiment, researchers implanted a pig liver into a brain-dead patient, and the organ remained functional for 10 days without immediate rejection. While it didn’t fully match human liver functionality, it processed bile and essential proteins, showing potential for temporary use in liver failure patients.
U.S. and China Lead Xenotransplantation Efforts
The U.S. has also been pioneering xenotransplants. The first human pig organ transplants were temporary, but two recent U.S. patients—one from Alabama and another from New Hampshire—are still doing well after receiving pig kidneys. Clinical trials for wider use are expected soon.
What’s Next for Pig Organ Transplants?
Scientists continue to explore ways to refine these procedures. Some U.S. researchers are experimenting with external pig livers as “bridge” solutions, helping filter the blood of patients with failing livers—similar to dialysis for kidney failure, as reported by Associated Press.
Experts, however, urge caution. “This is a promising first step, but we still have more questions than answers,” said Dr. Parsia Vagefi, a liver transplant specialist at UT Southwestern Medical Center.
The Future of Xenotransplantation
Organ shortages across the world have led to an opportunity for genetically modified pig organs to become life-saving alternatives. The recent transplant achievements represent an essential breakthrough for medical science that will provide hope to millions who need help.